ODCs

Click node...

5 associated genes
17 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
No signs/symptoms info

Hypothyroidism due to deficient transcription factors involved in pituitary development or function

Ring dermoid of cornea


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	PROP1	(0.52)	PITX2

Citations in the biomedical literature:

Hypothyroidism due to deficient transcription factors involved in pituitary development or function		Ring dermoid of cornea
	Synonym(s): (no synonyms)		Synonym(s): - Ring dermoid syndrome

	Classification (Orphanet): - Rare endocrine disease - Rare genetic disease		Classification (Orphanet): - Rare eye disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Neoplasms -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C535684

Hypothyroidism due to deficient transcription factors involved in pituitary development or function
	Very frequent - Absent / hypotonic / flaccid abdominal wall muscles - Asthenia / fatigue / weakness - Coarse face - Constipation - Face / facial anomalies - Failure to thrive / difficulties for feeding in infancy / growth delay - Hepatitis / icterus / cholestasis - Hypothyroidy - Hypotonia - Large fontanelle / delayed fontanelle closure - Sleep and vigilance disorders - Umbilical hernia Frequent - Cleft lip and palate - Hypothalamic-hypophyseal axis functional anomalies / hypopituitarism - Intellectual deficit / mental / psychomotor retardation / learning disability - Septo-optic dysplasia - Short stature / dwarfism / nanism
Ring dermoid of cornea
(no data available)